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In 2019 Gast was elected a Fellow of the Royal Academy of Engineering (FREng).

Most recently, Alice Gast's involvement in Chevron has been heavily criticised by students as part of the "Divest Imperial" campaign in 2019 and 2020. The student-led campaign has the aim to divest Imperial College resources from arms, tobacco and fossil fuels and to craft a new investment policy as a community. In protests, parts of the student body have requested that Alice Gast should either resign from her position at Chevron or her position at Imperial College.

In 2018 it was reported that Alice Gast became one of the highest earning leaders of any British university receiving a salary of £433,000 per year. This has been criticised as excessive, particularly in light of the academic's pension strike that occurred in the same year.

In 2017 she became a Fellow of The City and Guilds of London Institute.

Alice Petry Gast FREng (born May 25, 1958) is an American researcher who is the 16th president of Imperial College London in London, United Kingdom. She became Imperial's president on 1 September 2014. An internationally renowned scholar, researcher and academic leader, Gast was named one of the top 100 “Modern Era” engineers in the country under the category of “Leadership” by the American Institute of Chemical Engineers.

Gast was named president of Imperial College London on 3 January 2014, taking up post on 1 September 2014. She succeeded Keith O'Nions. As president, Gast leads the college's strategy, including the development of its new 25-acre campus, Imperial West, and its links to government, industry, philanthropists and alumni.

In April 2012 Imperial's governing council agreed to separate into two the role of the rector (the head of the university), and create the senior positions of president and provost.

When the transition to the new model and the search for its new senior positions began in 2012, the title changed to president & rector. Now that the provost has been appointed and the transition is complete, Gast is known as president.

In October 2012, Gast was elected to the board of directors of the Chevron Corporation, one of the world's leading integrated energy companies, with subsidiaries that conduct business worldwide. Gast will serve on the company's audit committee.

In 2012, the Council on Competitiveness held a two-day conference at Lehigh, titled “Leveraging the Talent Development Process to Drive Innovation.” The conference was sponsored by the council, Lehigh, and Air Products.

In 2011 the automotive executive Lee Iacocca, an alumnus of Lehigh University, gave $5 million in endowment to support the creation of a new international internship program. It provides an array of international work experiences for Lehigh students that include international co-ops, research experiences, and internships or cohort internships. The cohort internships are led by a Lehigh faculty member that matches Lehigh students with their peers from another country to work as a team on a common problem within a multinational corporation. Gast commented that the gift would "provide opportunities for our students to gain a deeper understanding of the unique challenges that exist in an interdependent and highly connected global society".

In 2011, Lehigh joined top schools across the country as a part of an innovative program focused on reducing high-risk drinking behaviors as a part of the National Institute on Alcohol Abuse and Alcoholism (NIAAA). In 2010, Gast was named to the NIAAA College Presidents’ council.

In February 2011, a 16-member panel of scientists led by Gast released a report after reviewing the scientific evidence related to the FBI investigation of the anthrax letters mailed in the aftermath of the September 11 attacks in 2001. Anthrax spores contained in the letters were mailed across the country and were responsible for killing five people and sickening 17 others.

Gast is a member of the U.S. Manufacturing Competitiveness Initiative Steering Committee, and in 2011, she joined other national leaders in Washington, D.C. for the 25th anniversary of the Council on Competitiveness, a day marked by the public release of the council's long-awaited strategy to improve American competitiveness and spur economic recovery through increased manufacturing.

In 2010, Gast shared her educational expertise at the Lord Dearing Memorial Conference, a forum for accomplished educators to shape the debate on the future of education. Gast presented in a session discussing the global economic crisis and higher education.

In 2010, Gast was selected as one of three new science envoys by Secretary of State Hillary Clinton. Gast was charged with encouraging U.S. global engagement in science and technology. She has traveled to the Central Asian and Caucasus regions, including Kazakhstan, Uzbekistan, and Azerbaijan. She has advised the White House, the State Department and the U.S. scientific community about the knowledge and insights she has gained from her travels and interactions.

In June 2010, Gast received an honorary degree from the University of Western Ontario at their 295th Convocation. She also has received honorary degrees from Notre Dame, the Universiti Teknologi Malaysia, and the University of Pierre and Marie Curie. In 2017 she received an honorary professorship from Tsinghua University.

In mid-April, 2009, Gast moved forward on a commitment to the environment by pledging to make environmental sustainability and climate change an institutional priority at the university. Gast signed the Lehigh University Climate Commitment at an Earth Day celebration.

In March 2009, Gast authored an op ed that appeared in Science magazine, in which she sounded a note of caution in the way that the short-term funding for scientific research contained in the U.S. economic stimulus package will be spent.

Long-term research and education provide innovative, creative discoveries that spur transformative change, Gast noted. "The United States needs to start making the down payment on this exploration, knowing that the needed breakthroughs cannot be generated within the next two years. As science funding agencies begin awarding their one-time money, they must be mindful of the sustainability of their programs. The recent signing of the fiscal year 2009 omnibus bill with its 4.7% increase for agencies funding science and technology R&D is a welcome sign. Maintaining that momentum in the coming years will be essential."

The panel declared that it was not possible to reach a definitive conclusion about the origins of the anthrax in letters based on the science alone. Gast stated in a news conference that "We find the scientific evidence to be consistent with their conclusions but not as definitive as stated". She emphasized that this case rested on the complex interface between science and the law enforcement investigation. The panel convened in 2008 after the FBI asked the National Research Council to form a group to conduct an independent review of the scientific approaches, methodologies and analytical techniques used in its investigation and to determine whether the FBI reached appropriate scientific conclusions. The FBI's investigation connected the letter materials to a flask in the lab of a researcher at the U.S. Army Medical Research Institute for Infectious Diseases (USAMRIID).

Gast and Gansler co-authored an op-ed in the July 11, 2008 issue of the Chronicle of Higher Education, citing a concern that the unintended effects of restrictive federal government policies on scientific research include impeding the nation's ability to be economically competitive and defend itself against potential threats.

In October, 2008, Gast was named one of the top 100 "Modern Era" engineers in the country, under the category of "Leadership" by the American Institute of Chemical Engineers.

From August 2006 to August 2014, Gast was the 13th president of Lehigh University. Gast is not the first Lehigh president recruited from MIT. In 1895 they invited Thomas Messinger Drown to take the presidency, for whom Drown Hall is named. In November 2010, Lehigh's board of trustees voted to reappoint Gast to a second five-year term through 2016.

In 2006, Gast co-chaired (with Jacques S. Gansler, vice president for research, University of Maryland) a non-partisan committee that produced an extensive report on "Science and Security in a Post 911 World: A Report Based on Regional Discussions Between the Science and Security Communities Committee on a New Government" (University Partnership for Science and Security) that was published by the National Academy of Sciences.

In recognition of her achievements, Gast has received numerous awards and honors including the NAS Award for Initiatives in Research, the Colburn Award of the American Institute of Chemical Engineers, the Camille and Henry Dreyfus Teacher Scholar Award and a Guggenheim Fellowship. In 1998 she received the Humboldt Research Award. She was elected to the National Academy of Engineering in 2001 and the American Academy of Arts and Sciences in 2002. She was named an AAAS Fellow in early 2007.

Born in Houston, Texas, US, Gast graduated as valedictorian from the University of Southern California in 1980 with a B.Sc. in chemical engineering. She completed her postgraduate work at Princeton University, receiving a M.A. (1981) and Ph.D. (1984) in chemical engineering, with thesis titled A Study of Polymer-Induced Phase Transitions in Colloidal Suspensions and was a Hertz Fellow. She spent a postdoctoral year completing a NATO fellowship at the École Supérieure de Physique et de Chimie Industrielles in Paris. From 1985 to 2001 she taught at Stanford University, and then moved to the Massachusetts Institute of Technology, where she served as the vice president for research and associate provost until her appointment as Lehigh University president in 2006.