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Liston was elected in the general election on November 6, 2018, winning 57 percent of the vote over 43 percent of Republican candidate Stu Harris, flipping the seat from Republican control to Democratic control.

After completing her studies in 2006, Beth Liston joined the faculty at The Ohio State University as an Assistant Professor in the Department of Internal Medicine, Division of Hospital Medicine. She has since been caring for hospitalized adults and children at both Ohio State Wexner Medical Center and Nationwide Children's Hospital. In 2012, Liston was promoted to Associate Professor and in 2018 promoted to full Professor of Clinical Medicine based on her research and national reputation for developing curricula in the fields of clinical reasoning and inter-professional collaboration. Liston is one of only a handful of Professors in Hospital Medicine across the nation, and the only of over 100 doctors in her Division to achieve this rank.

Liston was born on Long Island, New York and moved to Columbus at the age of 8. Growing up in Worthington, she attended Linworth Alternative High School as well as Thomas Worthington High School and graduated as Salutorian in 1992. Liston was awarded the Glenna R Joyce Scholarship which included a full scholarship to study at the University of Notre Dame where she graduated Magna Cum Laude in 1996 with a degree in Biochemistry. After graduating from Notre Dame, Liston enrolled in a dual MD/PhD program at The Ohio State University. Her PhD research was focused on the molecular biology of cancer chemo-prevention. In 2002, Liston graduated Cum Laude earning both an MD and PhD. For her accomplishments in medical studies, she was inducted into Alpha Omega Alpha Medical Honor Society. Liston completed her medical residency training at Yale New Haven Hospital between 2002 and 2006 and is currently Board Certified in both Internal Medicine and Pediatrics.

Beth Wagner Liston (born October 26, 1974) is an American doctor and politician who is the member of the Ohio House of Representatives from the 21st district in Franklin County. Ohio House District 21 includes Dublin, Worthington, and parts of Northwest Columbus. Liston is currently serving her first term as a State Representative.