As a teenager, Carina worked in a supermarket selling ceramic dishes when she decided to appear for a casting in Canal 13. But her profile did not give to play a role in the soap opera Amigovios, since at 20 she was very big for the cast, but too small to enter the role of teacher. However, the door that was closed, was the same that made her way as a television actress. A representative summoned her to meet her and together they went to the channel. Carina was offered to do a test, she improvised a monologue and they were fascinated. Days later a call would kick her off in her colossal career as a television actress; Alejandro Romay, the "Zar de la televisión" wanted to sign a contract with her. The fiction chosen was a soap opera of Canal 9. In the year 1995, she was selected to put herself in the shoes of the beautiful and evil Carla Lucero, a character who catapulted her as actress, and especially as villain actress. Her role was scheduled only for a couple of months, however it lasted a year and a half. And his Carla Lucero, the good one that became very bad, passed without identity change to Ricos y famosos, soap opera starring Natalia Oreiro and Diego Ramos. Her character was on the air for two consecutive years, consecrating it as one of the most remembered and recognized bad ones of the Argentine television. For her character she received the award Viva in 2000 to the best soap opera villain, in Israel. In the year 1998, she participated as a guest actress, playing Vera Vázquez, in Gasoleros, a soap opera of Canal 13. In the year 1999, she co-starred in the unit Por el nombre de Dios, with Alfredo Alcon and Adrián Suar. And in 2000 she was Mercedes, in Calientes, also from Canal 13 and Pol-ka, respectively. Between 2000 and 2001 she was selected to put herself in the shoes of María Méndez, protagonist of the soap opera Luna salvaje was broadcast by Telefe. That was her first protagonist as a fiction couple with the actor Gabriel Corrado. In the year 2002, the beautiful actress played Lucía Ledesma in Franco Buenaventura, el profe character who fell in love with her literature teacher, played by Osvaldo Laport. But because her co-leading role was overturned by the character of Celeste Cid, she left the cycle midway through the season. In the year 2004, she returns to play a villain in Padre Coraje. In mid 2005, Carina Zampini is integrated to the leading cast of the soap opera Hombres de honor, starring Gabriel Corrado and Laura Novoa. The following year she played Romina Franccini, protagonist of Collar de Esmeraldas, along with Osvaldo Laport, and produced by Ideas del Sur for the afternoons of Canal 13. In the year 2008 she returned to television, in the second season of Mujeres de nadie, in the character of Dr. Fernanda Almirón, another villain. A pediatrician who suffers from bipolarity and double personality. She participated in the theater play Flores de Acero, in Julia's character, along with Irma Roy, Nora Cárpena, Dorys Del Valle, María Rosa Fugazot and Mercedes Funes. With the direction in charge of Julio Baccaro. In the year 2010 she was in the comedy Rumores, with Nicolás Vázquez, Reina Reech, Andrea Frigerio, Diego Pérez, Eunice Castro, Carlos Calvo and Marcelo de Bellis. It tells the story of four couples attending a mansion on the outskirts of New York to celebrate the 30th anniversary of the marriage of one of them. In the year 2010 she returned to with Malparida, playing Martina Figueroa, counterfigure of the villain Juana Viale. Between 2012 and 2013 she starred with Sebastián Estevanez the soap opera Dulce Amor playing Victoria Bandi, a businesswoman who owns a candy empire. Due to the success of the soap opera Dulce Amor, producer Quique Estevanez summons her again to be the protagonist of Camino al Amor along with Sebastián Estevanez and again on the screen of Telefe. On June 29, 2015 she debuted as a television presenter in the morning cycle, Morfi, todos a la mesa, next to Gerardo Rozín on the screen of Telefe. During 2017 she led the reality show Despedida de Solteros with Marley. Currently, she host the television show El gran premio de la cocina with Juan Marconi on the screen of Canal 13.