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On February 26, 2018, Hoskins announced his resignation with immediate effect as an MPP and as Minister of Health & Long-Term Care.

On June 20, 2018, Prime Minister Justin Trudeau appointed Hoskins to head a national pharmacare strategy.

Hoskins was re-elected in June 2014, and was appointed by Kathleen Wynne as the Minister of Health and Long Term Care.

Hoskins resigned on November 9, 2012, to stand as a candidate in the Ontario Liberal Party leadership election. He was eliminated after the first ballot and he endorsed Kathleen Wynne, the eventual winner. On February 11, 2013, he was appointed Minister of Economic Development, Trade & Employment.

In the 2011 Ontario election, Hoskins was easily re-elected defeating PC candidate Christine McGirr by 16,076 votes. After the election he was appointed as Minister of Children and Youth Services.

On January 18, 2010, he was named the Minister of Citizenship and Immigration in Dalton McGuinty's second government.

On August 12, 2009, Hoskins was nominated as the provincial Liberal candidate in the St. Paul's by-election. On September 19, 2009, he defeated Toronto Sun columnist Sue-Ann Levy running for the Progressive Conservatives.

A medical doctor and former president of War Child Canada, Hoskins was made an Officer of the Order of Canada in 2008 for his humanitarian work.

In April 2008, Hoskins was made an Officer of the Order of Canada by Governor General Michaëlle Jean for his humanitarian work. At the age of 33, Hoskins became the youngest recipient of the United Nations Association in Canada's Lester B. Pearson Peace Medal and was later awarded the Meritorious Service Cross by the Governor General of Canada in the name of the Queen of Canada for his work in war-torn communities around the world.

On April 21, 2007, Hoskins was chosen as the Liberal candidate in the riding of Haldimand—Norfolk for the 2008 Federal election. On October 14, 2008, he was defeated by Conservative incumbent Diane Finley.

Hoskins and his wife, Samantha Nutt, received Honorary Doctorates of Law from McMaster University in May 2005 for their work promoting human rights and their role in delivering humanitarian assistance to some of the world's most vulnerable populations. Hoskins also has honorary degrees from Brock and Niagara Universities.

In 1997, Hoskins joined the Ministry of Foreign Affairs as Lloyd Axworthy's Senior Policy Advisor. While at the Department of Foreign Affairs, he was responsible for contributing to Canadian foreign policy in the areas of human rights, human security, humanitarian affairs, peace building, war-affected children and Africa.

From 1987 to 1990, Hoskins lived and worked in Sudan providing humanitarian relief to Ethiopian refugees in eastern Sudan, and to displaced civilians in southern Sudan. In 1991, Hoskins co-founded the International Study Team, and led a group of international experts to examine the impact of war on the civilian population in Iraq. The study provided a detailed humanitarian assessment of post-Gulf War Iraq.

Eric William Hoskins OC MSC (born November 29, 1960) is a former politician in Ontario, Canada. He was a Liberal member of the Legislative Assembly of Ontario from 2009 to 2018 who represented the electoral district of Toronto—St. Paul's. He served as a cabinet minister in the governments of Dalton McGuinty and Kathleen Wynne in the portfolios of Health and Long-Term Care (2009 – 2018), Economic Development, Trade, and Employment (2013 – 2014), Children and Youth Services (2011 – 2012), and Citizenship and Immigration (2010 - 2011). In 2013 he contended for the leadership of the Ontario Liberal Party, which was won by Kathleen Wynne. Hoskins resigned from cabinet and the legislature on February 26, 2018, three months before the provincial election. On June 20, 2018, the federal government announced that Hoskins had been appointed Chair of the Advisory Council on the Implementation of National Pharmacare.

Hoskins was born on November 29, 1960, in Simcoe, Ontario. After he attended Simcoe Composite School for high school, Hoskins completed a Bachelor of Science degree in chemistry at McMaster University in 1982 and graduated with a Doctor of Medicine degree from McMaster University Medical School in 1985. Subsequently, Hoskins was awarded a Rhodes scholarship and continued his studies at the University of Oxford where he completed a Doctor of Philosophy degree in public health and epidemiology. Hoskins also holds a Master of Science degree from the London School of Hygiene & Tropical Medicine and a postgraduate diploma in health economics from The University of Aberdeen. He is a fellow of the Royal College of Physicians and Surgeons of Canada and is board-certified in the speciality of Community Medicine (now referred to as Public Health and Preventive Medicine).