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In July 2018, an extensive exhibition entitled DeathLAB: Democratizing Death opened at the 21st Century Museum of Contemporary Art in Kanazawa, Japan and will run until March 2019. The exhibition includes video loops of DeathLAB's Manifesto/Imperative, several design projects, and a series of edited and curated interviews conducted over the past two years.

In 2014, Karla Rothstein's design of a commercial space that featured custom fabricated concrete blocks cast in flour sacks was recognized by Built by Women New York City and the American Institute of Architects New York. In 2015, Latent's Constellation Park project placed third in an international competition on new ways of memorializing the dead. A model of the project was sold by Christie's at a charity auction and is currently on display at Sir John Soane's Museum in London. Constellation Park was featured in New York Magazine's 2016 Reasons to Love New York issue. Her most notable work was Verboten, a 10,000 square foot night club in Brooklyn, New York. Current projects include the design and development of 25 units of affordable housing in Brownsville, Brooklyn, awarded through the New York City Department of Housing Preservation and Development, the design of environmentally-advanced civic infrastructure to replace urban cemeteries, an environmentally-conscious childcare facility in New York City, a prototype for a resilient small scale building in a Rockaways flood zone, and the conversion of a 240,000 square foot former mill in the Berkshires called Greylock Works, among others. Greylock Works is little more than two years into a renovation process that will transform the former industrial site converted into a mixture of food production, residential, hotel and restaurant space. The project was recently awarded a substantial grant of $1.72 million from the Massachusetts State Secretary of Housing and Economic Development.

Rothstein's first built work was "Ballston Lake House" in Saratoga, New York, developed with Joel Towers, which is anchored by 150,000 pounds of precast concrete. It was the only US house included in the book "In DETAIL: Single Family Houses" (Birkhäuser, 2000) in addition to being counted among notable architecture historian Kenneth Frampton's anthology of American Masterworks (Rizzoli, 2008).

Karla Rothstein received a Bachelor of Architecture from the University of Maryland, School of Architecture in 1988 and a Master of Architecture from Columbia University's Graduate School of Architecture, Planning and Preservation (GSAPP) in 1992. While at GSAPP, Karla participated in exchange programs in Russia and Switzerland, receiving Certificates of Academic Exchange from the Moscow Institute of Architecture in 1989 and the Eidgenössische Technische Hochschule (ETH) in 1991. Prior to co-founding her own architecture practice, Rothstein worked as an international coordinating architect for William McDonough and Ralph Appelbaum & Associates.

Supported as a Jacob Javits Fellow in Fine Arts from 1988–1992, a William Kinne Traveling Fellow in 1992, and a NYFA recipient in 2000, Rothstein's professional and academic work has been featured and/or exhibited at Storefront for Art and Architecture, Rensselaer Polytechnic Institute, Barnard College, Columbia University, Van Alen Institute, Max Protetch Gallery, the Center for Architecture, Gizmodo, Architecture Magazine, Casabella, The New York Times, Financial Times, The Wall Street Journal, and WIRED, Japan.

Karla Maria S. Rothstein (born 1966) is an American architect and adjunct Associate Professor at Columbia Graduate School of Architecture, Planning and Preservation, where she is also the founder and director of Columbia University's trans-disciplinary DeathLAB Rothstein is also the co-founder of Latent Productions, an architecture, research, and development firm in New York City, which she co-founded in 1999 with Salvatore Perry. A significant focus of her architecture practice, research, and teaching has been redefining urban spaces of death and remembrance.