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On 27 June 2018, the University of Stirling, Scotland, conferred on him the degree of Doctor of the University "for Patrick McGrath's outstanding support of academic research."

Professor Emeritus of Creative Writing at Princeton, Joyce Carol Oates, makes the case that McGrath is transcribing the "nightmares of the 'shattered personality' that resonate within us all," calling his short stories "masterful and seductive, ... Bold, original, and disquieting tales are told by narrators who are themselves bizarre (a boot, a fly—to name just two) and are in most cases omniscient."

McGrath also worked as a teacher of creative writing to undergraduate and graduate students at the University of Texas at Austin in the fall semester of 2006. He also taught craft courses for a number of years in the MFA program at Hunter College, New York, and since 2007, has taught an MFA program at the New School in New York.

Three of McGrath's novels and one of his stories have been adapted into films, two of which adaptations (Spider, 2002 and The Grotesque, 1995) were written by McGrath himself. The film adaptation for Asylum, 2005 was written by Patrick Marber and a short film made of The Lost Explorer from Blood and Water and Other Tales was adapted by Tim Walker. From The Wardrobe Mistress to the current unnamed novel-in-progress on the Spanish Civil War, McGrath shows increased interest in the fascistic tendencies in international politics and its effects on the psychology of characters.

His novel Martha Peake won the Premio Flaiano Prize in Italy and Asylum was shortlisted for the 1996 Guardian Fiction Prize.

He has lived in various parts of North America and also spent several years on a remote island in the North Pacific, before finally settling in New York City in 1981.

McGrath was born in London and grew up near Broadmoor Hospital from the age of five where his father was Medical Superintendent. He was educated at a Jesuit boarding school in Windsor from the age of thirteen, before moving to another Jesuit public school, Stonyhurst College in Lancashire, upon the closure of his first school. In 1967, at the age of sixteen, he ran away from this institution to London. He graduated from the Birmingham College of Commerce with an honours degree in English and American literature in 1971, awarded externally by the University of London, before his father found him a job later that year in Penetang, Ontario working in the Oakridge top-security unit of the Penetang Mental Health Centre.

Patrick McGrath (born 7 February 1950) is a British novelist, whose work has been categorised as gothic fiction.